Menopause
Multi-Symptom Relief
- HORMONE-FREE*
- NON-PRESCRIPTION
A menopause symptom relief supplement that helps with symptoms by using S-equol, a plant-based ingredient derived from soy that mimics estrogen- relieving hot flashes and more. Ease of use: one supplement for menopause relief that targets multiple symptoms. 1-6†

Simple, plant-based menopause relief. Guaranteed.
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TWO TABLETS DAILY
Discover how 2 tablets daily can make all the difference in 90 days or less. -
MADE WITH PLANT-BASED S-EQUOL
Equelle is powered by 10 mg of S-equol.View Full Ingredients List -
LOVE IT OR IT’S ON US
If Equelle doesn’t work for you, we’ll refund you in full with our 90 day money-back guarantee.

Achieve optimal results in 90 days or less
daily for 90 days
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Day 30: Signs of Menopause Symptom Relief
You may be able to notice fewer hot flashes and supported sleep. -
Month 2: Building Momentum
Your symptoms may continue to improve. If you’re not feeling the full effect, hang in there! -
Month 3: Feel like yourself Again!
You may be enjoying relief from hot flashes, muscle aches, and poor sleep quality.1,2,4†⁋|| -
Month 4 & Beyond
Consistency is the key to success! Remember fluctuations in symptoms is normal and can be triggered by changes in lifestyle. Stick with it to maintain optimal results!
How Equelle works using S-equol
S-equol is a metabolite of a soy isoflavone fermented from soy germ that shares a similar molecular structure to estrogen.
This allows it to mimic some of the beneficial effects of estrogen to alleviate some of the most bothersome menopausal symptoms.6†
FAQs
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S-equol is the key ingredient in Equelle. It is a plant-based compound produced through the fermentation of soy germ and is naturally produced by some women in the gut in small amounts after consuming soy.
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Equelle’s key ingredient, S-equol, has undergone decades of scientific research. It has been studied to be safe in clinical trials.
In general, taking botanicals or other supplements may result in possible gastrointestinal upset. We recommend taking Equelle with food if you experience stomach sensitivity with supplements.
If you are experiencing any other adverse effects, we recommend discontinuing product use and consulting your physician or healthcare professional. Please also contact us at hello@equelle.com. -
Equelle’s formulation contains calcium, which is recommended to be taken separately from both iron and thyroid medications for proper absorption. For specific guidance, we recommend the following: Iron Supplements and/or Multivitamins Containing Iron: take 1-2 hours apart from Equelle. Thyroid Medication: take Equelle 4 hours apart from your thyroid medication.
We always recommend you discuss any supplement use with your doctor. -
Only a small amount of soy is in Equelle. This amount is significantly less than the amount in a single serving of common soy foods.
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No. Since Equelle contains soy, Equelle should not be taken if you have a soy allergy or sensitivity.
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Key Ingredient: S-equol
Inactive Ingredients: Dicalcium Phosphate, Fermented Soy Germ, Silicon Dioxide, Croscarmellose Sodium, Magnesium Stearate, Coating (Hypromellose, Glycerin, Hydroxypropyl Cellulose), Microcrystalline Cellulose.
Contains Soy
Real reviews fromreal women.
Reviews represent individual experiences and may not reflect clinical results. Individual results may vary. Equelle is a dietary supplement to provide menopause support, such as relieving hot flashes and muscle aches, improving sleep quality, and supporting healthy bones†1-5⁋||
- Reviews
- Questions
Surprised
My experience has been good. I still get some hot flashes. I sleep better. The surprise, since I have been taking Equelle, I have not had to tend to unwanted facial hair as a often as I did before. ☺️
Menopause Complete Support
My joints and muscles feel good. Nine months in and hot flashes are almost nonexistent. My sleep quality is good as well.